![]() ![]() 119-123 of the 8th edition) would be a safe and sanity-preserving step. However, for the purposes of CICM exam preparation, limiting oneself to the dead space measurement section from Nunn's (p. The single best peer-reviewed resource for this topic is probably Roberts (2015). Alveolar dead space can be calculated from the difference between the physiological and anatomical dead space volumes.The graph of nitrogen concentration over volume can be used to calculate the anatomical dead space.The exhaled breath has its volume and nitrogen concentration measured.The oxygen replaces nitrogen in the anatomical dead space.A single breath of 100% oxygen is given to the subject.Anatomical dead space can be measured using the Fowler method.As the result, the Enghoff dead space is generally larger than the Bohr dead space.The Enghoff modification of the Bohr equation uses arterial CO 2 instead of alveolar CO 2, and is therefore easier to measure, but it is influenced by multiple factors, such as:.The equation is, V D/V T = (F ACO 2 - F ECO 2) / F ACO 2.The Bohr equation can be used to determine physiological dead space from the difference between the exhaled CO 2 and alveolar CO 2, but the latter is hard to measure.Physiological dead space can be measured using the Bohr-Enghoff method. ![]()
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